Clay B Walker

Clay B Walker,

Associate Dean For Faculty Affairs

Department: DN-ORAL BIOLOGY
Business Phone: (352) 273-8866
Business Email: cwalker@dental.ufl.edu

Teaching Profile

Courses Taught
2006-2007,2009-2017
DEN5127 Infectious Diseases
2011-2012,2014
DEN6416C Basic Sciences Rev
2013-2014
DEN6681 Craniofacial Pathobiology
2011-2012
GMS6161 Introduction to Oral Biology II
2009
DEN8290 Special Topics
2007
DEN5121 Biochm Molec Cell Bio

Publications

2021
Bacterial Biofilm Growth on Various Dental Stabilization Systems for Avulsed and Luxated Teeth
Applied Sciences-Basel. 11(19) [DOI] 10.3390/app11198982.
2021
Stability of healthy subgingival microbiome across space and time.
Scientific reports. 11(1) [DOI] 10.1038/s41598-021-03479-2. [PMID] 34907334.
2018
The subgingival microbiome in patients with established rheumatoid arthritis.
Rheumatology (Oxford, England). 57(7):1162-1172 [DOI] 10.1093/rheumatology/key052. [PMID] 29562298.
2015
Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis.
Applied and environmental microbiology. 81(2):783-93 [DOI] 10.1128/AEM.02712-14. [PMID] 25398868.
2013
Pathogenicity of exopolysaccharide-producing Actinomyces oris isolated from an apical abscess lesion.
International endodontic journal. 46(2):145-54 [DOI] 10.1111/j.1365-2591.2012.02099.x. [PMID] 22900599.
2013
Periodontal treatment reduces matrix metalloproteinase levels in localized aggressive periodontitis.
Journal of periodontology. 84(12):1801-8 [DOI] 10.1902/jop.2013.130002. [PMID] 23537121.
2012
Microbiological characterization in children with aggressive periodontitis.
Journal of dental research. 91(10):927-33 [PMID] 22863892.
2011
A comparative evaluation of the sealing ability of 2 root-end filling materials: an in vitro leakage study using Enterococcus faecalis.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 112(2):e74-7 [DOI] 10.1016/j.tripleo.2011.01.030. [PMID] 21507688.
2011
Comparison of the virulence of exopolysaccharide-producing Prevotella intermedia to exopolysaccharide non-producing periodontopathic organisms.
BMC infectious diseases. 11 [DOI] 10.1186/1471-2334-11-228. [PMID] 21864411.
2011
Reduction of two red complex bacteria by sustained-release doxycycline and correlation to improvement in mean pocket depth.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995). 32(3):e32-7 [PMID] 23738858.
2010
Comparison of bacterial reduction in straight and curved canals using erbium, chromium:yttrium-scandium-gallium-garnet laser treatment versus a traditional irrigation technique with sodium hypochlorite.
Journal of endodontics. 36(4):725-8 [DOI] 10.1016/j.joen.2009.11.017. [PMID] 20307752.
2010
Genetic analysis of mobile tetQ elements in oral Prevotella species.
Anaerobe. 16(6):604-9 [DOI] 10.1016/j.anaerobe.2010.08.008. [PMID] 20826220.
2010
Perpetuation of Subgingival Biofilms in An in Vitro Model
Molecular oral microbiology. 25(1):81-87 [DOI] 10.1111/j.2041-1014.2009.00549.x. [PMID] 20331796.
2010
Treating chronic periodontitis: current status, challenges, and future directions.
Clinical, cosmetic and investigational dentistry. 2:79-91 [PMID] 23662085.
2009
Gene expression profile and pathogenicity of biofilm-forming Prevotella intermedia strain 17.
BMC microbiology. 9 [DOI] 10.1186/1471-2180-9-11. [PMID] 19146705.
2009
Preliminary assessment of safety and effectiveness in humans of ProBiora3, a probiotic mouthwash.
Journal of applied microbiology. 107(2):682-90 [DOI] 10.1111/j.1365-2672.2009.04243.x. [PMID] 19486429.
2008
Matrix metalloproteinase levels in children with aggressive periodontitis.
Journal of periodontology. 79(5):819-26 [DOI] 10.1902/jop.2008.070513. [PMID] 18454660.
2008
Modified-release subantimicrobial dose doxycycline enhances scaling and root planing in subjects with periodontal disease.
Journal of periodontology. 79(3):440-52 [DOI] 10.1902/jop.2008.070375. [PMID] 18315426.
2007
An in vitro biofilm model of subgingival plaque.
Oral microbiology and immunology. 22(3):152-61 [PMID] 17488440.
2007
Microbiologic changes following administration of locally delivered doxycycline in smokers: a 15-month follow-up.
Journal of periodontology. 78(11):2143-9 [PMID] 17970681.
2007
Subantimicrobial dose doxycycline effects on osteopenic bone loss: microbiologic results.
Journal of periodontology. 78(8):1590-601 [PMID] 17668979.
2005
Detection and characterization of beta-lactamase genes in subgingival bacteria from patients with refractory periodontitis.
FEMS microbiology letters. 242(2):319-24 [PMID] 15621454.
2005
Long-term treatment with sub-antimicrobial dose doxycycline has no antibacterial effect on intestinal flora.
Journal of clinical periodontology. 32(11):1163-9 [PMID] 16212578.
2004
Chemotherapeutics: antibiotics and other antimicrobials.
Periodontology 2000. 36:146-65 [PMID] 15330947.
2004
Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial.
Journal of periodontology. 75(8):1068-76 [PMID] 15455733.
2003
Effects of subantimicrobial-dose doxycycline in the treatment of moderate acne.
Archives of dermatology. 139(4):459-64 [PMID] 12707093.
2002
Rationale for use of antibiotics in periodontics.
Journal of periodontology. 73(10):1188-96 [PMID] 12416778.
2000
Long-term treatment with subantimicrobial dose doxycycline exerts no antibacterial effect on the subgingival microflora associated with adult periodontitis.
Journal of periodontology. 71(9):1465-71 [PMID] 11022777.
2000
The effects of sustained release doxycycline on the anaerobic flora and antibiotic-resistant patterns in subgingival plaque and saliva.
Journal of periodontology. 71(5):768-74 [PMID] 10872958.
1997
Antibiotic resistance in an oral isolate of Prevotella intermedia.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 25 Suppl 2:S281-3 [PMID] 9310707.
1996
Detection and prevalence of the tetracycline resistance determinant Tet Q in the microbiota associated with adult periodontitis.
Oral microbiology and immunology. 11(4):282-8 [PMID] 9002882.
1996
Refractory periodontitis or recurrence of disease.
Journal of clinical periodontology. 23(3 Pt 2):289-92 [PMID] 8707992.
1996
Selected antimicrobial agents: mechanisms of action, side effects and drug interactions.
Periodontology 2000. 10:12-28 [PMID] 9567935.
1996
The acquisition of antibiotic resistance in the periodontal microflora.
Periodontology 2000. 10:79-88 [PMID] 9567938.
1994
Treatment of subjects with refractory periodontal disease.
Journal of clinical periodontology. 21(9):628-37 [PMID] 7806681.
1993
A Role for Antibiotics in the Treatment of Refractory Periodontitis.
Journal of periodontology. 64 Suppl 8S:772-781 [DOI] 10.1902/jop.1993.64.8s.772. [PMID] 29539756.
1993
A role for antibiotics in the treatment of refractory periodontitis.
Journal of periodontology. 64(8 Suppl):772-81 [PMID] 8410617.
1993
Comparative analysis between a modified ultrasonic tip and hand instruments on clinical parameters of periodontal disease.
Journal of periodontology. 64(8):694-700 [PMID] 8410606.
1993
Current Status of Systemic Antibiotic Usage in Destructive Periodontal Disease.
Journal of periodontology. 64 Suppl 8S:760-771 [DOI] 10.1902/jop.1993.64.8s.760. [PMID] 29539750.
1993
Sequencing of a tet(Q) gene isolated from Bacteroides fragilis 1126.
Antimicrobial agents and chemotherapy. 37(9):2037-41 [PMID] 7916585.
1992
Identification of a streptomycin resistance gene and a partial Tn3 transposon coding for a beta-lactamase in a periodontal strain of Eikenella corrodens.
Antimicrobial agents and chemotherapy. 36(4):740-3 [PMID] 1323951.
1992
Phenotypic characteristics and DNA relatedness in Prevotella intermedia and similar organisms.
Oral microbiology and immunology. 7(1):60-4 [PMID] 1528627.
1992
The effect of 3 mouthrinses on plaque and gingivitis development.
Journal of clinical periodontology. 19(1):19-23 [PMID] 1310096.
1991
Clinical, microbiological and immunological characteristics of subjects with “refractory” periodontal disease.
Journal of clinical periodontology. 18(5):291-9 [PMID] 2066442.
1990
Localization and identification of root canal bacteria in clinically asymptomatic periapical pathosis.
Journal of endodontics. 16(11):534-8 [PMID] 2084210.
1989
Effect of non-surgical periodontal therapy combined with adjunctive antibiotics in subjects with “refractory” periodontal disease. (I). Clinical results.
Journal of clinical periodontology. 16(10):647-53 [PMID] 2693498.
1989
Efficacy of Perimed antibacterial system on established gingivitis. (I). Clinical results.
Journal of clinical periodontology. 16(10):630-5 [PMID] 2693495.
1988
Microbiological effects of mouthrinses containing antimicrobials.
Journal of clinical periodontology. 15(8):499-505 [PMID] 3053791.
1985
Antibiotic Susceptibilities of Periodontal Bacteria: In Vitro Susceptibilities to Eight Antimicrobial Agents.
Journal of periodontology. 56 Suppl 11S:67-74 [DOI] 10.1902/jop.1985.56.11s.67. [PMID] 29538943.
1985
Efficacy of Clindamycin Hydrochloride in Refractory Periodontitis: 12-Month Results.
Journal of periodontology. 56 Suppl 11S:75-80 [DOI] 10.1902/jop.1985.56.11s.75. [PMID] 29538955.

Grants

Mar 2015 – Mar 2017
An examination of the oral microflora of arthritic subjects
Role: Principal Investigator
Funding: US DEPT OF VET AFF NEBRASKA-WESTERN IA
Nov 2014 – Jun 2017
Microbiota associated with arthritic patients with and without periodontitis
Role: Principal Investigator
Funding: UNIV OF NEBRASKA

Contact Details

Phones:
Business:
(352) 273-8866
Emails:
Addresses:
Business Mailing:
PO Box 100424
OFC DG 48
GAINESVILLE FL 32610
Business Street:
DG-48 JHMHC
GAINESVILLE FL 32611