Bernadett Papp

Bernadett Papp, Ph.D.

Assistant Professor

Department: DN-ORAL BIOLOGY
Business Phone: (352) 294-8752
Business Email: bpapp@dental.ufl.edu

Teaching Profile

Courses Taught
2019-2025
GMS6193 Research Conference in Oral Biology
2018
DEN8290 Special Topics
2021
GMS6162 Oral Microbiology and Immunology

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0001-5352-3946

Publications

Academic Articles
2024
Conserved linear motif within the immediate early protein ORF45 promotes its engagement with KSHV lytic cycle-promoting forkhead transcription factors, FOXK1 and FOXK2
Journal of Virology. 98(10) [DOI] 10.1128/jvi.00886-24. [PMID] 39287387.
2024
Genome-Wide Transcriptional Roles of KSHV Viral Interferon Regulatory Factors in Oral Epithelial Cells
Viruses. 16(6) [DOI] 10.3390/v16060846. [PMID] 38932139.
2023
Hypoxia and HIF-1α promote lytic de novo KSHV infection
Journal of Virology. 97(11) [DOI] 10.1128/jvi.00972-23. [PMID] 37909728.
2023
Kaposi’s Sarcoma-Associated Herpesvirus Immediate Early Proteins Trigger FOXQ1 Expression in Oral Epithelial Cells, Engaging in a Novel Lytic Cycle-Sustaining Positive Feedback Loop
Journal of Virology. 97(3) [DOI] 10.1128/jvi.01696-22. [PMID] 36815831.
2023
KSHV RTA utilizes the host E3 ubiquitin ligase complex RNF20/40 to drive lytic reactivation
Journal of Virology. 97(11) [DOI] 10.1128/jvi.01389-23. [PMID] 37888983.
2022
KSHV RTA Induces Degradation of the Host Transcription Repressor ID2 To Promote the Viral Lytic Cycle.
Journal of virology. 96(12) [DOI] 10.1128/jvi.00101-22. [PMID] 35604218.
2022
The ORF45 Protein of Kaposi’s Sarcoma-Associated Herpesvirus and Its Critical Role in the Viral Life Cycle
Viruses. 14(9) [DOI] 10.3390/v14092010. [PMID] 36146816.
2021
Clinical Manifestations and Epigenetic Regulation of Oral Herpesvirus Infections
Viruses. 13(4) [DOI] 10.3390/v13040681. [PMID] 33920978.
2020
A protein assembly mediates Xist localization and gene silencing
Nature. 587(7832):145-151 [DOI] 10.1038/s41586-020-2703-0. [PMID] 32908311.
2020
Comparative analysis of the viral interferon regulatory factors of KSHV for their requisite for virus production and inhibition of the type I interferon pathway.
Virology. 541:160-173 [DOI] 10.1016/j.virol.2019.12.011. [PMID] 32056714.
2020
Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV.
PLoS pathogens. 16(1) [DOI] 10.1371/journal.ppat.1008268. [PMID] 31923286.
2020
Publisher Correction: A protein assembly mediates Xist localization and gene silencing
Nature. 586(7830):E30-E30 [DOI] 10.1038/s41586-020-2790-y.
2019
Genome-Wide Identification of Direct RTA Targets Reveals Key Host Factors for Kaposi’s Sarcoma-Associated Herpesvirus Lytic Reactivation.
Journal of virology. 93(5) [DOI] 10.1128/JVI.01978-18. [PMID] 30541837.
2017
Inhibition of the lytic cycle of Kaposi’s sarcoma-associated herpesvirus by cohesin factors following de novo infection.
Virology. 512:25-33 [DOI] 10.1016/j.virol.2017.09.001. [PMID] 28898712.
2016
LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection.
PLoS pathogens. 12(9) [DOI] 10.1371/journal.ppat.1005878. [PMID] 27606464.
2014
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency.
Cell. 159(7):1681-97 [DOI] 10.1016/j.cell.2014.11.040. [PMID] 25525883.
2013
Epigenetics of reprogramming to induced pluripotency.
Cell. 152(6):1324-43 [DOI] 10.1016/j.cell.2013.02.043. [PMID] 23498940.
2013
Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins.
Cell reports. 3(6):2113-26 [DOI] 10.1016/j.celrep.2013.05.015. [PMID] 23791530.
2012
Pluripotency re-centered around Esrrb.
The EMBO journal. 31(22):4255-7 [DOI] 10.1038/emboj.2012.285. [PMID] 23064149.
2011
Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape.
Cell research. 21(3):486-501 [DOI] 10.1038/cr.2011.28. [PMID] 21321600.
2010
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis.
Genome research. 20(2):155-69 [DOI] 10.1101/gr.099796.109. [PMID] 19952138.
2007
A genetic screen identifies novel polycomb group genes in Drosophila.
Genetics. 176(4):2099-108 [PMID] 17717194.
2006
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.
Genes & development. 20(9):1110-22 [PMID] 16618800.

Grants

Aug 2024 ACTIVE
Role of FOXK subfamily in KSHV infection
Role: Other
Funding: NATL INST OF HLTH NIDCR
Aug 2022 – May 2024
Gene regulatory role of vIRF1 in KSHV infection
Role: Other
Funding: NATL INST OF HLTH NIDCR
Aug 2022 – Aug 2023
KSHV ORF45 subcellular localization and its impact on transcriptional reprogramming of oral cells
Role: Other
Funding: AMER ASSO FOR DENTAL RES
Jul 2021 – Jul 2022
The role of herpesvirus tegument proteins in primary infection of oral epithelial cells
Role: Other
Funding: AMER ASSO FOR DENTAL RES
Jul 2021 – May 2023
Forkhead factor regulation in oral viral infection
Role: Other
Funding: NATL INST OF HLTH NIDCR
Dec 2020 ACTIVE
Immune evasion mechanisms by a tumor herpesvirus in the oral cavity
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Jan 2019 – Dec 2023
Controlling the Establishment of Oncogenic Herpesviral Infection
Role: Co-Investigator
Funding: AMERICAN CANCER SOCIETY
Sep 2018 – Aug 2020
Genomic characterization of Forkhead factors in oral infection
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Jun 2018 – May 2024
Viral and host strategies for regulation of KSHV infection
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2017 – May 2019
OR-DRPD-ROF2017: Immune evasion mechanisms during oral infection by an oncogenic herpesvirus
Role: Co-Investigator
Funding: UF DSR OPPORTUNITY FUND
Jan 2017 – Dec 2018
Functional dissection of the mechanism that lead to loss of somatic cell identity
Role: Principal Investigator
Funding: NATL INST OF HLTH NICHD

Contact Details

Phones:
Business:
(352) 294-8752
Emails:
Addresses:
Business Mailing:
PO Box 100424
GAINESVILLE FL 32610
Business Street:
1395 CENTER DRIVE, D4-38B
GAINESVILLE FL 32606