Tridib Ganguly

Tridib Ganguly, Ph.D.

Research Assistant Scientist

Department: DN-ORAL BIOLOGY
Business Phone: (352) 273-8850
Business Email: tganguly@ufl.edu

About Tridib Ganguly

Dr. Ganguly received his M.S. in biochemistry from University of Calcutta, India and his Ph.D. from Bose Institute, India. He then joined as a faculty fellow in the Indian Institute of Science Education to continue his research before joining Wake Forest University to study Bordetella pertussis virulence regulation as a postdoc. He joined Lemos-Abranches laboratory in 2016 and worked primarily on the regulation of the oxidative stress response regulator Spx. He was promoted to Research Assistant Scientist in 2019 and is currently focused on understanding the interplay between oxidative stress and metal homeostasis in S. mutans.

Publications

2021
Amyloid Aggregation of Streptococcus mutans Cnm Influences Its Collagen-Binding Activity.
Applied and environmental microbiology. 87(21) [DOI] 10.1128/AEM.01149-21. [PMID] 34406827.
2021
Increased Oxidative Stress Tolerance of a Spontaneously Occurring perR Gene Mutation in Streptococcus mutans UA159.
Journal of bacteriology. 203(8) [DOI] 10.1128/JB.00535-20. [PMID] 33526613.
2021
Zinc import mediated by AdcABC is critical for colonization of the dental biofilm by Streptococcus mutans in an animal model.
Molecular oral microbiology. 36(3):214-224 [DOI] 10.1111/omi.12337. [PMID] 33819383.
2020
Manganese Uptake, Mediated by SloABC and MntH, Is Essential for the Fitness of Streptococcus mutans.
mSphere. 5(1) [DOI] 10.1128/mSphere.00764-19. [PMID] 31915219.
2020
PepO is a target of the two-component systems VicRK and CovR required for systemic virulence of Streptococcus mutans.
Virulence. 11(1):521-536 [DOI] 10.1080/21505594.2020.1767377. [PMID] 32427040.
2020
Phenotypic and Genotypic Characterization of Streptococcus mutans Strains Isolated from Endodontic Infections.
Journal of endodontics. 46(12):1876-1883 [DOI] 10.1016/j.joen.2020.09.002. [PMID] 32919986.
2020
Regulatory circuits controlling Spx levels in Streptococcus mutans.
Molecular microbiology. 114(1):109-126 [DOI] 10.1111/mmi.14499. [PMID] 32189382.
2018
CovR and VicRKX Regulate Transcription of the Collagen Binding Protein Cnm of Streptococcus mutans.
Journal of bacteriology. 200(23) [DOI] 10.1128/JB.00141-18. [PMID] 30201780.
2018
Disruption of a Novel Iron Transport System Reverses Oxidative Stress Phenotypes of a dpr Mutant Strain of Streptococcus mutans.
Journal of bacteriology. 200(14) [DOI] 10.1128/JB.00062-18. [PMID] 29735760.
2017
Transcriptome responses of Streptococcus mutans to peroxide stress: identification of novel antioxidant pathways regulated by Spx.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-16367-5. [PMID] 29167560.
2015
The protein BpsB is a poly-β-1,6-N-acetyl-D-glucosamine deacetylase required for biofilm formation in Bordetella bronchiseptica.
The Journal of biological chemistry. 290(37):22827-40 [DOI] 10.1074/jbc.M115.672469. [PMID] 26203190.
2014
Comparative analyses of a cystic fibrosis isolate of Bordetella bronchiseptica reveal differences in important pathogenic phenotypes.
Infection and immunity. 82(4):1627-37 [DOI] 10.1128/IAI.01453-13. [PMID] 24470470.
2014
The Bordetella pertussis Bps polysaccharide enhances lung colonization by conferring protection from complement-mediated killing.
Cellular microbiology. 16(7):1105-18 [DOI] 10.1111/cmi.12264. [PMID] 24438122.
2013
D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing.
Journal of bacteriology. 195(22):5102-11 [DOI] 10.1128/JB.00510-13. [PMID] 24013634.
2012
Biochemical characterization of L1 repressor mutants with altered operator DNA binding activity.
Bacteriophage. 2(2):79-88 [PMID] 23050218.
View on: PubMed
2012
BpsR modulates Bordetella biofilm formation by negatively regulating the expression of the Bps polysaccharide.
Journal of bacteriology. 194(2):233-42 [DOI] 10.1128/JB.06020-11. [PMID] 22056934.
2012
Interaction of chandipura virus N and P proteins: identification of two mutually exclusive domains of N involved in interaction with P.
PloS one. 7(4) [DOI] 10.1371/journal.pone.0034623. [PMID] 22485180.
2010
Characterization of an unusual cold shock protein from Staphylococcus aureus.
Journal of basic microbiology. 50(6):519-26 [DOI] 10.1002/jobm.200900264. [PMID] 20806243.
2010
Elucidation of functional domains of Chandipura virus Nucleocapsid protein involved in oligomerization and RNA binding: implication in viral genome encapsidation.
Virology. 407(1):33-42 [DOI] 10.1016/j.virol.2010.07.032. [PMID] 20727566.
2010
Regions and residues of an asymmetric operator DNA interacting with the monomeric repressor of temperate mycobacteriophage L1.
Biochemistry. 49(19):4235-43 [DOI] 10.1021/bi9020956. [PMID] 20377203.
2010
Stabilization of the primary sigma factor of Staphylococcus aureus by core RNA polymerase.
BMB reports. 43(3):176-81 [PMID] 20356457.
View on: PubMed
2009
Antagonistic effects Na+ and Mg2+ on the structure, function, and stability of mycobacteriophage L1 repressor.
BMB reports. 42(5):293-8 [PMID] 19470244.
View on: PubMed
2009
Moderately thermostable phage Phi11 Cro repressor has novel DNA-binding capacity and physicochemical properties.
BMB reports. 42(3):160-5 [PMID] 19336003.
View on: PubMed
2009
Physicochemical properties and distinct DNA binding capacity of the repressor of temperate Staphylococcus aureus phage phi11.
The FEBS journal. 276(7):1975-85 [DOI] 10.1111/j.1742-4658.2009.06924.x. [PMID] 19250317.
2008
Overexpression of a delayed early gene hlg1 of temperate mycobacteriophage L1 is lethal to both M. smegmatis and E. coli.
BMB reports. 41(5):363-8 [PMID] 18510866.
View on: PubMed
2007
Detection of antistaphylococcal and toxic compounds by biological assay systems developed with a reporter Staphylococcus aureus strain harboring a heat inducible promoter – lacZ transcriptional fusion.
Journal of biochemistry and molecular biology. 40(6):936-43 [PMID] 18047789.
View on: PubMed
2007
Purification and characterization of repressor of temperate S. aureus phage phi11.
Journal of biochemistry and molecular biology. 40(5):740-8 [PMID] 17927908.
View on: PubMed
2007
Repressor of temperate mycobacteriophage L1 harbors a stable C-terminal domain and binds to different asymmetric operator DNAs with variable affinity.
Virology journal. 4 [PMID] 17598887.
View on: PubMed
2006
Effects of physical, ionic, and structural factors on the binding of repressor of mycobacteriophage L1 to its cognate operator DNA.
Protein and peptide letters. 13(8):793-8 [PMID] 17073724.
View on: PubMed
2004
A point mutation at the C-terminal half of the repressor of temperate mycobacteriophage L1 affects its binding to the operator DNA.
Journal of biochemistry and molecular biology. 37(6):709-14 [PMID] 15607030.
View on: PubMed
2004
Cloning and sequencing analysis of the repressor gene of temperate mycobacteriophage L1.
Journal of biochemistry and molecular biology. 37(2):254-9 [PMID] 15469704.
View on: PubMed

Contact Details

Phones:
Business:
(352) 273-8850
Emails:
Business:
tganguly@ufl.edu