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UF Health University of Florida
College of Dentistry UNIVERSITY of FLORIDA
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About Overview

Marcelle Nascimento, D.D.S., M.S., Ph.D.

Department of Restorative Dental SciencesPhoto of Marcelle Nascimento

Division of Operative Dentistry

Associate Professor

Dental Science Building, Rm D9-5
P.O. Box 100415
Gainesville, FL 32610-0424
Phone: 352-273-5858
Email: mnascimento@dental.ufl.edu

Education

  • Postdoctoral (2005–2007): Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Fla., USA.
  • Ph.D. in Cariology (2002–2005): School of Dentistry of Piracicaba, University of Campinas, São Paulo, Brazil.
  • M.S. in Cariology (2000–2002): School of Dentistry of Piracicaba, University of Campinas, São Paulo, Brazil.
  • D.D.S.(1996–2000): School of Dentistry of Piracicaba, University of Campinas, São Paulo, Brazil.

Professional Experience

2015 to present
Associate Professor with Tenure
Department of Restorative Dental Sciences, Division of Operative Dentistry, College of Dentistry, University of Florida, Gainesville, Fla., USA
2007–2015
Assistant Professor
Department of Operative Dentistry, College of Dentistry, University of Florida, Gainesville, Fla., USA
2006–2007
Adjunct Clinical Assistant Professor
Department of Operative Dentistry, College of Dentistry, University of Florida, Gainesville, Fla., USA
2005–2007
Post-Doctoral Associate
Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Fla., USA
2004–2005
Assistant Professor
Department of Microbiology, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil

Publications

Monographs
  • Nascimento, M.M. Physiologic and genetic characterization of Streptococcus sobrinus. 2005. School of Dentistry of Piracicaba, University of Campinas, São Paulo, Brazil.
  • Nascimento, M.M. Clinical and microbiological aspects of root caries. 2002. School of Dentistry of Piracicaba, University of Campinas, São Paulo, Brazil.
Referred Publications (most recent)
  1. Nascimento, MM, Alvarez AJ, Huang X, Browngardt C,  Jenkins R, Sinhoreti MC, Ribeiro APD, Dilbone DA, Richards VP , Garrett TJ, Burne RA. Metabolic profile of supragingival plaque exposed to arginine and fluoride. Journal of Dental Research 2019; 98(11):1245-1252.
  1. Lee K, Walker AR, Chakraborty B, Kaspar JR, Nascimento MM, Burne RA. Exploring novel probiotic mechanisms of StreptococcusA12 with functional genomics. Applied and Environmental Microbiology; 2019 85(21). pii: e01335-19.
  1. Nascimento MM. Approaches to modulate biofilm ecology. Dental Clinics of North America, 2019; 63(4):581-594.
  2. Guzmán-Armstrong S, Fontana M, Nascimento MM, Ferreira Zandona AG. Dental caries: evidence and interdisciplinary person-centered care considerations for management over time. Dental Clinics of North America, 2019; 63(4):xiii-xv. 
  1. Nascimento MM, Alvarez AJ, Huang X, Hanway S, Perry S, Luce A, Richards VP, Burne RA. Arginine Metabolism in Supragingival Oral Biofilms as a Potential Predictor of Caries Risk.  Journal of Dental Research Clinical and Translational Research 2019; 4(3):262-270.
  1. Urquhart O, Tampi MP, Pilcher L, Slayton RL, Araujo MWB,Fontana M, Guzmán-Armstrong S, Nascimento MM, Nový BB, Tinanoff N, Weyant RJ, Wolff MS, Young DA, Zero DT, Brignardello-Petersen R, Banfield L, Parikh A, Joshi G, Carrasco-Labra A. Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. Journal of Dental Research 2018; 98(1):14-26.
  1. Slayton RL, Urquhart O, Araujo MWB, Fontana M, Guzmán-Armstrong S, Nascimento MM, Nový BB, Tinanoff N, Weyant RJ, Wolff MS, Young DA, Zero DT, Tampi MP, Pilcher L, Banfield L, Carrasco-Labra A. Evidence-based clinical practice guideline on nonrestorative treatments for carious lesions. Journal of the American Dental Association 2018, 149 (10): 837-849.
  1. Velsko IM, Chakraborty B, NascimentoMM, Burne RA, Richards VP. Species Designations Belie Phenotypic and Genotypic Heterogeneity in Oral Streptococci. mSystems. 2018; 3(6), pii: e00158-18.
  1. Dilbone D, Feng X, Su Y, Xirau-Probert P, Behar-Horenstein L,Nascimento MM. Influence of preparatory workshops on dental students’ academic performance and stress on their first Operative Dentistry psychomotor exam. Journal of Dental Education 2018, 82(6):608-613. 
  1. Nascimento MM. Potential uses of arginine in dentistry. Advances in Dental Research 2018, 29(1): 98-103. 
  1. Nascimento MM. Oral microbiota transplant: a potential new therapy for oral diseases. Journal of the California Dental Association 2017, 45(10): 565-568.
  1. Huang X, Browngardt CM, Jiang M, Ahn SJ, Burne RA, Nascimento MM. Diversity in antagonistic interactions between commensal oral streptococci and Streptococcus mutans. Caries Research 2018, 52(1-2): 88-101.
  1. Richards VP*, Alvarez AJ, Luce AR, Perry S, Hong H, Shaddox LM, Burne RA, Nascimento MM*. The microbiome of site-specific dental plaque of children with different caries status. Infection and Immunity 2017, 85(8) e00106-117. (*equal contribution as 1st authors).
  1. Geraldeli S, Soares EF, Alvarez AJ, Tanaz F, Sinhoreti MAC, Batich CD, Nascimento MM. A new arginine-based dental adhesive system: formulation, mechanical and antimicrobial properties. Journal of Dentistry 2017, 63: 72-70. 
  1. Nascimento MM, Zaura E, Mira AA, Takahashi N, Ten Cate JM. Second Era of OMICS in Caries Research: moving past the phase of disillusionment. Journal of Dental Research 2017, 96(7): 733-740. 
  1. Nascimento MM, Behar-Horenstein LS, Feng X, Guzmán-Armstrong S, Fontana M. Exploring how U.S. dental schools teach removal of carious tissues during cavity preparations. Journal of Dental Education 2017, 81(1): 5-13.
  1. Brinkman C, Adewumi A, Gong Y, Huang H, Weinstein D, Nascimento MM, Shaddox LM. Microbial profile of supragingival and subgingival plaque of patients with glycogen storage disease. Journal of Inborn Errors of Metabolism and Screening 2016, 4: 1-6. 
  1. Nascimento MM, Mugayar L, Tomar SL, Garvan CW, Catanalotto FA, Behar-Horenstein, L. The impact of an infant oral health program in pre-doctoral dental education. Journal of Dental Education 2016, 80(11): 1328-1336. 
  1. Nascimento MM, Dilbone D, Pereira P, Duarte WR, Geraldeli S, Delgado AJ. Abfraction lesions: etiology, diagnosis and treatment options. Clinical, Cosmetic and Investigational Dentistry 2016, 8:79-87.
  1. Huang X, Palmer PS, Ahn SJ, Richards VP, Williams ML, Nascimento MM, Burne RA. A highly arginolytic Streptococcus species that potently antagonizes Streptococcus mutans. Applied Environmental Microbiology 2016, 82(7): 2187-2201.
  1. Bezerra DS, Stipp RN, Neves BG, Guedes SFF, Nascimento MM, Rodrigues LKA. Insights into the virulence traits of Streptococcus mutans in dentine carious lesions of children with early childhood caries. Caries Research 2016, 50: 279-287.
  1. Behar-Horenstein L, Catalanotto FA, Nascimento MM. Anticipated and actual implementation of case-based learning by dental faculty members during and after training. Journal of Dental Education 2015, 79(9): 1049-1060.
  1. Dilbone D, Wynkoop B, Delgado A, Nascimento MM, Echeto L, Behar-Horenstein L. Clinical assessment in Operative Dentistry. MedEdPORTAL 2016, 12:10369.
  1. Huang X, Schulte RM, Burne RA, Nascimento MM. Characterization of the arginolytic microflora provides insights into pH homeostasis in human oral biofilms. Caries Research 2015, 49:165-176.

Research Grants

  • NIH/NIDCR – K23 DE023579: 2014-2019
    “Alkali production and Caries Prevention in Children”
    Role: Principal Investigator
  • Colgate-Palmolive: 2015-2016 “The Metabolomics of Oral Biofilms exposed to Arginine and Fluoride”        Role: Principal Investigator
  • Colgate-Palmolive: 2009-2015 “The Microbiology of Caries Resistance”
    Role: Principal Investigator
  • NIH/NIDCR – R01 DE021789: 2012-2016
    “Functional Amyloid Formation in Streptococcus mutans”
    Role: Investigator
  • NIH/NIDCR-DE10362: 2010-2013
    “Molecular Biology of Oral Alkali Generation”
    Role: Investigator
  • NIH/ NIDCR-R21 DE018392: 2008-2009
    “Alkali production in human plaque and saliva as predictor of caries risk”
    Role: Co-Principal Investigator
  • NIH/ NIDCR-U01-DE 16746 and U01-DE 16747: 2007-2009
    “DPBRN: Reasons for placement of the first restoration”
    Role: Investigator
  • FAPESP-Brazil: 2002-2004
    Doctoral fellowship: “Physiologic and genetic characterization of Streptococcus sobrinus.”
    Role: Principal Investigator
  • FAPESP-Brazil: 2003
    Postgraduate exchange fellowship: “The adaptive acid tolerance response of    Streptococcus sobrinus”
    Role: Principal Investigator
  • FAPESP-Brazil: 2000-2002
    Master fellowship: “Clinical and microbiological aspects of root caries”
    Role: Principal Investigator
  • FAPESP-Brazil: 1999-2000
    Undergraduate research fellowship: “Quantitative analysis of microlinkage in posterior         teeth restored with composite using different insertions techniques”
    Role: Principal Investigator
  • CNPq-Brazil: 1996–1998
    Undergraduate research fellowship – University of Campinas, São Paulo, Brazil.
    “Morphological study of the Tropidurus torquatus specie tooth structure”
    Role: Principal Investigator