Department of Orthodontics
- Basic Science
- Pain mechanisms related to the effects of age on pain sensitivity
- The role of changes in immune function, HPA axis, and different transmitter systems on varying sensitivity to pain in animals of different ages
- How these changes are affected during normal aging, under pathological conditions and during conditions of stress are also being investigated
- Interest is in evaluating these changes using complex behavioral assessment strategies that involve cortical processing and decision making; plasticity and glia responses to acute and chronic pain conditions at different ages and the impact of cytokines and other inflammatory molecules in the development of chronic pain conditions.