Robert A. Burne, Ph.D.

Associate Dean for Research
Distinguished Professor and Chair

Department of Oral Biology
1395 Center Drive, D5-26
Box 100424
Gainesville, FL. 32610-0424
Phone: 352-273-8847
E-Mail: rburne@dental.ufl.edu

 

 

  • Ph.D., University of Rochester, Microbiology and Immunology, 1987
  • B.S., Pennsylvania State University, Microbiology, 1981

Main Interests

The primary interests in my laboratory are in the molecular mechanisms governing the ability of bacteria that are capable of causing diseases in humans to modulate their virulence in response to environmental influences. To accomplish this, a variety of microbiological, biochemical, and recombinant DNA technologies are employed. These include the use of continuous culture techniques to tightly control growth parameters of bacteria, coupled with the use of genetically-engineered bacteria and gene fusion technology, which allows for a detailed molecular analysis of gene expression in response to specific stimuli. These systems are also being utilized for identifying and characterizing signal transduction systems and cis– and trans– acting factors controlling bacterial virulence expression. In addition, there is a major commitment to studying bacterial biofilms grown in custom-fabricated bioreactors using gene fusion techniques and confocal laser microscopy. The specific projects in the lab are focused in four major areas. The first is a detailed study of the genetics and physiology of polysaccharide metabolism and its relationship to virulence and biofilm formation by oral streptococci. The second project is a molecular genetic analysis of the role of the stress regulon in control of gene expression. The third project is a broad-based approach to understanding the genetics and physiology of ureases and arginine metabolism by streptococci and actinomycetes. The final project utilizes a multi-species biofilm model system coupled with the use of genetically engineered bacteria to explore microbial ecology and the pathogenesis of polymicrobial infectious diseases.

Publications

  • Kim JN, Burne RA. CcpA and CodY Coordinate Acetate Metabolism in Streptococcus mutans. Appl Environ Microbiol. 2017 Jan 27. pii: AEM.03274-16. doi: 10.1128/AEM.03274-16. PMID: 28130304
  • Kaspar J, Kim JN, Ahn SJ, Burne RA. An Essential Role for (p)ppGpp in the Integration of Stress Tolerance, Peptide Signaling, and Competence Development in Streptococcus mutans.
    Front Microbiol. 2016 Jul 28;7:1162. doi: 10.3389/fmicb.2016.01162.
  • Shields RC, Burne RA.Growth of Streptococcus mutans in Biofilms Alters Peptide Signaling at the Sub-population Level.Front Microbiol. 2016 Jul 15;7:1075. doi: 10.3389/fmicb.2016.01075.
  • Moye ZD, Son M, Rosa-Alberty AE, Zeng L, Ahn SJ, Hagen SJ, Burne RA.Effects of Carbohydrate Source on Genetic Competence in Streptococcus mutans.Appl Environ Microbiol. 2016 Jul 15;82(15):4821-34. doi: 10.1128/AEM.01205-16.
  • Zeng L, Farivar T, Burne RA.Amino Sugars Enhance the Competitiveness of Beneficial Commensals with Streptococcus mutans through Multiple Mechanisms.Appl Environ Microbiol. 2016 May 31;82(12):3671-82. doi: 10.1128/AEM.00637-16.
  • Huang X, Palmer SR, Ahn SJ, Richards VP, Williams ML, Nascimento MM, Burne RA.A Highly Arginolytic Streptococcus Species That Potently Antagonizes Streptococcus mutans. Appl Environ Microbiol. 2016 Jan 29;82(7):2187-201. doi: 10.1128/AEM.03887-15.
  • Zeng L, Burne RA.Sucrose- and Fructose-Specific Effects on the Transcriptome of Streptococcus mutans, as Determined by RNA Sequencing.Appl Environ Microbiol. 2015 Oct 16;82(1):146-56. doi: 10.1128/AEM.02681-15.
  • Son M, Shields R, Ahn SJ, Burne RA, Hagen SJ. Bidirectional signaling in the competence regulatory pathway of Streptococcus mutans. FEMS Microbiol Lett. 2015 Sep 10.
  • Zeng L, Burne RA. NagR differentially regulates the expression of the glmS and nagAB genes required for amino sugar metabolism by Streptococcus mutans. J Bacteriol. 2015 Aug 31.
  • Shields RC, Burne RA. Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and S. mutans. FEMS Microbiol Lett. 2015 Aug;362(16)
  • Mogen AB, Chen F, Ahn SJ, Burne RA, Wang D, Rice KC. Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms. PLoS One. 2015 Jul 29;10(7)
  • Palmer SR, Burne RA. Post-transcriptional regulation by distal Shine-Dalgarno sequences in the grpE-dnaK intergenic region of Streptococcus mutans. Mol Microbiol. 2015 Jul 14.
  • Son M, Ghoreishi D, Ahn SJ, Burne RA, Hagen SJ. Sharply Tuned pH Response of Genetic Competence Regulation in Streptococcus mutans: a Microfluidic Study of the Environmental Sensitivity of comX. Appl Environ Microbiol. 2015 Aug 15;81(16):5622-31.
  • Kim JN, Ahn SJ, Burne RA. Genetics and Physiology of Acetate Metabolism by the Pta-Ack Pathway of Streptococcus mutans. Appl Environ Microbiol. 2015 Aug;81(15):5015-25.
  • Huang X, Schulte RM, Burne RA, Nascimento MM. Characterization of the arginolytic microflora provides insights into pH homeostasis in human oral biofilms. Caries Res. 2015;49(2):165-76.
  • Kaspar J, Ahn SJ, Palmer SR, Choi SC, Stanhope MJ, Burne RA. A unique open reading frame within the comX gene of Streptococcus mutans regulates genetic competence and oxidative stress tolerance. Mol Microbiol. 2015 May;96(3):463-82.
  • Moye ZD, Zeng L, Burne RA. Fueling the caries process: carbohydrate metabolism and gene regulation by Streptococcus mutans. J Oral Microbiol. 2014 Sep 5;6.
  • Seaton K, Ahn SJ, Burne RA. Regulation of competence and gene expression in Streptococcus mutans by the RcrR transcriptional regulator. Mol Oral Microbiol. 2015 Apr;30(2):147-59.
  • Ahn SJ, Kaspar J, Kim JN, Seaton K, Burne RA. Discovery of novel peptides regulating competence development in Streptococcus mutans. J Bacteriol. 2014 Nov;196(21):3735-45.
  • Huang SC, Burne RA, Chen YY. The pH-dependent expression of the urease operon in Streptococcus salivarius is mediated by CodY. Appl Environ Microbiol. 2014 Sep;80(17):5386-93.
  • Moye ZD, Burne RA, Zeng L. Uptake and metabolism of N-acetylglucosamine and glucosamine by Streptococcus mutans. Appl Environ Microbiol. 2014 Aug;80(16):5053-67.
  • Liao S, Klein MI, Heim KP, Fan Y, Bitoun JP, Ahn SJ, Burne RA, Koo H, Brady LJ, Wen ZT. Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the protein secretion machinery. J Bacteriol. 2014 Jul;196(13):2355-66
  • Richards VP, Palmer SR, Pavinski Bitar PD, Qin X, Weinstock GM, Highlander SK, Town CD, Burne RA, Stanhope MJ. Phylogenomics and the dynamic genome evolution of the genus Streptococcus. Genome Biol Evol. 2014 Apr;6(4):741-53.
  • Nascimento MM, Browngardt C, Xiaohui X, Klepac-Ceraj V, Paster BJ, Burne RA. The effect of arginine on oral biofilm communities. Mol Oral Microbiol. 2014 Feb;29(1):45-54
  • Moye ZD, Zeng L, Burne RA. Modification of gene expression and virulence traits in Streptococcus mutans in response to carbohydrate availability. Appl Environ Microbiol. 2014 Feb;80(3):972-85.
  • Guo Q, Ahn SJ, Kaspar J, Zhou X, Burne RA. Growth phase and pH influence peptide signaling for competence development in Streptococcus mutans. J Bacteriol. 2014 Jan;196(2):227-36.
  • Nascimento MM, Liu Y, Kalra R, Perry S, Adewumi A, Xu X, Primosch RE, Burne RA. Oral arginine metabolism may decrease the risk for dental caries in children. J Dent Res. 2013 Jul;92(7):604-8.
  • Palmer SR, Miller JH, Abranches J, Zeng L, Lefebure T, Richards VP, Lemos JA, Stanhope MJ, Burne RA. Phenotypic heterogeneity of genomically-diverse isolates of Streptococcus mutans. PLoS One. 2013 Apr 16;8(4):e61358.
  • Kim JN, Stanhope MJ, Burne RA. Core-gene-encoded peptide regulating virulence-associated traits in Streptococcus mutans. J Bacteriol. 2013 Jun;195(12):2912-20
  • Zeng L, Choi SC, Danko CG, Siepel A, Stanhope MJ, Burne RA. Gene regulation by CcpA and catabolite repression explored by RNA-Seq in Streptococcus mutans. PLoS One. 2013;8(3):e60465
  • Zeng L, Xue P, Stanhope MJ, Burne RA. A galactose-specific sugar: phosphotransferase permease is prevalent in the non-core genome of Streptococcus mutans. Mol Oral Microbiol. 2013 Aug;28(4):292-301.
  • Cornejo OE, Lefébure T, Bitar PD, Lang P, Richards VP, Eilertson K, Do T, Beighton D, Zeng L, Ahn SJ, Burne RA, Siepel A, Bustamante CD, Stanhope MJ. Evolutionary and population genomics of the cavity causing bacteria Streptococcus mutans. Mol Biol Evol. 2013 Apr;30(4):881-93.
  • Zeng L, Burne RA. Comprehensive mutational analysis of sucrose-metabolizing pathways in Streptococcus mutans reveals novel roles for the sucrose phosphotransferase system permease. J Bacteriol. 2013 Feb;195(4):833-43
  •  Liu YL, Nascimento M, Burne RA. Progress toward understanding the contribution of alkali generation in dental biofilms to inhibition of dental caries. Int J Oral Sci. 2012 Sep;4(3):135-40.
  •  Ahn SJ, Qu MD, Roberts E, Burne RA, Rice KC. Identification of the Streptococcus mutans LytST two-component regulon reveals its contribution to oxidative stress tolerance. BMC Microbiol. 2012 Sep 1;12:187.
  • Burne RA, Zeng L, Ahn SJ, Palmer SR, Liu Y, Lefebure T, Stanhope MJ, Nascimento MM. Progress dissecting the oral microbiome in caries and health. Adv Dent Res. 2012 Sep;24(2):77-80.
  • Son M, Ahn SJ, Guo Q, Burne RA, Hagen SJ. Microfluidic study of competence regulation in Streptococcus mutans: environmental inputs modulate bimodal and unimodal expression of comX. Mol Microbiol. 2012 Oct;86(2):258-72.
  • Zeng L, Martino NC, Burne RA. Two gene clusters coordinate galactose and lactose metabolism in Streptococcus gordonii. Appl Environ Microbiol. 2012 Aug;78(16):5597-605.
  • Kim JN, Ahn SJ, Seaton K, Garrett S, Burne RA. Transcriptional organization and physiological contributions of the relQ operon of Streptococcus mutans. J Bacteriol. 2012 Apr;194(8):1968-78.
  • Bitoun JP, Liao S, Yao X, Ahn SJ, Isoda R, Nguyen AH, Brady LJ, Burne RA, Abranches J, Wen ZT. BrpA is involved in regulation of cell envelope stress responses in Streptococcus mutans. Appl Environ Microbiol. 2012 Apr;78(8):2914-22.
  • Morou-Bermúdez E, Billings RJ, Burne RA, Elías-Boneta A. Caries risk pyramid: a practical biological approach to caries management by risk assessment. P R Health Sci J. 2011 Dec;30(4):165-6.
  • Morou-Bermudez E, Elias-Boneta A, Billings RJ, Burne RA, Garcia-Rivas V, Brignoni-Nazario V, Suárez-Pérez E. Urease activity as a risk factor for caries development in children during a three-year study period: a survival analysis approach. Arch Oral Biol. 2011 Dec;56(12):1560-8.
  • Morou-Bermudez E, Elias-Boneta A, Billings RJ, Burne RA, Garcia-Rivas V, Brignoni-Nazario V, Suarez-Perez E. Urease activity in dental plaque and saliva of children during a three-year study period and its relationship with other caries risk factors. Arch Oral Biol. 2011 Nov;56(11):1282-9.
  • Bitoun JP, Nguyen AH, Fan Y, Burne RA, Wen ZT. Transcriptional repressor Rex is involved in regulation of oxidative stress response and biofilm formation by Streptococcus mutans. FEMS Microbiol Lett. 2011 Jul;320(2):110-7.
  • Liu Y, Burne RA. The major autolysin of Streptococcus gordonii is subject to complex regulation and modulates stress tolerance, biofilm formation, and extracellular-DNA release.J Bacteriol. 2011 Jun;193(11):2826-37.
  • Abranches J, Miller JH, Martinez AR, Simpson-Haidaris PJ, Burne RA, Lemos JA. The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cells. Infect Immun. 2011 Jun;79(6):2277-8
  • Zeng L, Das S, Burne RA. Genetic analysis of the functions and interactions of components of the LevQRST signal transduction complex of Streptococcus mutans. PLoS One. 2011 Feb 22;6(2):e17335.
  • Wen, Z. T., A. H. Nguyen, J. P. Bitoun, J. Abranches, H. V. Baker and R. A. Burne (2011) Transcriptome analysis of LuxS-deficient Streptocococc mutans grown in biofilms. Mol. Oral Microbiol. 26:2-18
  • Tong, H., L. Zeng and R. A. Burne (2011) The EIIABman permease regulates carbohydrate catabolite repression in Streptococcus gordonii. Appl. Environ. Microbiol.
  • Toro, E., M. M. Nascimento, E. Suarez-Perez, R. A. Burne, A. Elias-Boneta and E. Morou-Bermudez. (2010) The effect of sucrose on plaque and saliva urease levels in vivo. Arch. Oral. Biol. 55:249-254
  • Zeng, L., and R. A. Burne (2010) Seryl-phosphorylated HPr regulates CcpA-independent carbon catabolite repression in conjunction with PTS permeases in Streptococcus mutans. Mol. Microbiol. 75:1145-1158.
  • Zeng, L., S. Das and R. A. Burne (2010) Utilization of lactose and galactose by Streptococcus mutans: transport, toxicity and carbon catabolite repression. J. Bacteriol. 192:2434-2444.
  • Wen, Z. T., D. Yates, S-J. Ahn and R. A. Burne (2010) Biofilm formation and virulence expression by Streptococcus mutans are altered when grown in dual-species model. BMC Microbiology 10:111.
  • Ahn, S. J., K. C. Rice, J. Oleas, K. W. Bayles and R. A. Burne (2010) The Streptococcus mutans Cid and Lrg systems modulate virulence traits in response to multiple environmental signals. Microbiology 156:3136-3147.
  • Lemos, J. A., J. Abranches, H. Koo, R. E. Marquis and R. A. Burne (2010) Protocols to study the physiology of oral biofilms. Methods Mol. Biol. 666:87-102.
  • Seaton, K., S. J. Ahn, A. M. Sagstetter and R. A. Burne (2010) A transcriptional regulator and ABC transporters link stress tolerance (p)ppGpp and genetic competence. J. Bacteriol. 193:862-874
  • Griswold, A. R., M. M. Nascimento, and R. A. Burne (2009) Distrubution, regulation and role of the agmatine deiminase system in mutans streptococci. Oral Micro. Immunol. 24:79-82.
  • M. M. Nascimento, V.V. Gordan, C. W. Garvan, C. M. Browngardt, R. A. Burne (2009) Correlations of oral bacterial arginine and urea catabolism with caries experience. Oral Micro. Immunol. 24:89-95
  • Abranches, J. L. Zeng, M. Bélanger, P. H. Rodrigues, P. J. Simpson-Haidaris, D. Akin, W. A. Dunn Jr, A. Progulske-Fox, and R. A. Burne (2009) Invasion of human coronary artery endothelial cells by Streptococcus mutans OMZ175. Oral Microbiol. Immunol. 24:141-145.
  • Zeng, L., and R. A. Burne (2009) Transcriptional regulation of the cellobiose operon of Streptococcus mutans. J. Bacteriol. 191:2153-2162
  • Burne, R. A., S. J. Ahn, Z. T. Wen, L. Zeng, J. A. Lemos, J. Abranches and M. Nascimento. (2009) Opportunities for disrupting cariogenic biofilms. Adv. Dent. Res.
  • Ahn, S. J., S. J. Ahn and R. A. Burne (2009) Changes in biochemical and phenotypic properties of Streptococcus mutans growing with aeration. Appl. Environ. Microbiol. 75(8):2517-27
  • Liu, Y, L. Zeng and R. A. Burne (2009) AguR is required for induction of the Streptococcus mutans agmatine deiminase system by low pH and agmatine. Appl. Environ. Microbiol.
  • Liu, Y., and R. A. Burne (2009) Multiple two-component systems modulate alkali generation in Streptococcus gordonii in response to environmental stresses. J. Bacteriol. 191:7353-7362.
  • Liu, Y., and R. A. Burne (2009) Multiple two-component systems of Streptococcus mutans regulate agmatine deiminase gene expression and stress tolerance. J. Bacteriol. 191:7363-7366.
  • Lemos, J. A., M. M. Nascimento, V. K. Lin, J. Abranches and R. A. Burne. (2008) Global regulation by (p)ppGpp and CodY in Streptococcus mutans. J. Bacteriol. 190:5291-5299
  • Liu, Y, Y. Dong, M. Chen and R. A. Burne (2008) Environmental and growth phase regulation of the arginine deiminase genes of Streptococcus gordonii. Appl. Environ. Microbiol. 74:5023-5030.
  • Ahn, S. J., S. J. Ahn, Z. T. Wen, L. J. Brady and R. A. Burne (2008) Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva. Infect. Immun. 76:4259-4268
  • Zeng, L., and R. A. Burne (2008) Multiple sugar:phosphotransferase system permeases participate in catabolite modification of gene expression in Streptococcus mutans. Mol. Microbiol. 70:197-208.
  • Lemos, J. A., and R. A. Burne (2008) A model of efficiency: stress tolerance by Streptococcus mutans. Microbiology 154:3247-3255.
  • Abranches J, Nascimento MM, Zeng L, Browngardt CM, Wen ZT, Rivera MF, Burne RA. CcpA regulates central metabolism and virulence gene expression in Streptococcus mutans. J Bacteriol. 2008 Apr, 190(7):2340-9.
  • Chen YY, Feng CW, Chiu CF, Burne RA. cadDX operon of Streptococcus salivarius 57.I. Appl Environ Microbiol. 2008 Mar, 74(5):1642-5.
  • Nascimento MM, Lemos JA, Abranches J, Lin VK, Burne RA. Role of RelA of Streptococcus mutans in global control of gene expression. J Bacteriol. 2008 Jan,190(1):28-36.
  • Ahn SJ, Wen ZT, Burne RA. Effects of oxygen on virulence traits of Streptococcus mutans. J Bacteriol. 2007 Dec, 189(23):8519-27.
  • Ahn SJ, Burne RA. Effects of oxygen on biofilm formation and the AtlA autolysin of Streptococcus mutans. J Bacteriol. 2007 Sep, 189(17):6293-302.
  • Lemos JA, Lin VK, Nascimento MM, Abranches J, Burne RA. Three gene products govern (p)ppGpp production by Streptococcus mutans. Mol Microbiol. 2007 Sep, 65(6):1568-81.
  • Loeffler KA, Johnson TA, Burne RA, Antonelli PJ. Biofilm formation in an in vitro model of cochlear implants with removable magnets. Otolaryngol Head Neck Surg. 2007 Apr, 136(4):583-8.
  • Johnson TA, Loeffler KA, Burne RA, Jolly CN, Antonelli PJ. Biofilm formation in cochlear implants with cochlear drug delivery channels in an in vitro model. Otolaryngol Head Neck Surg. 2007 Apr, 136(4):577-82.
  • Lemos JA, Luzardo Y, Burne RA. Physiologic effects of forced down-regulation of dnaK and groEL expression in Streptococcus mutans. J Bacteriol. 2007 Mar;189(5):1582-8.
  • Burne RA, Bessen DE, Broadbent JR, Claverys JP. The Seventh International Conference on the Genetics of Streptococci, Lactococci, and Enterococci. J Bacteriol. 2007 Feb;189(4):1209-18.
  • Ahn SJ, Burne RA. The atlA operon of Streptococcus mutans: role in autolysin maturation and cell surface biogenesis. J Bacteriol. 2006 Oct, 188(19):6877-88.
  • Zeng L, Wen ZT, Burne RA. A novel signal transduction system and feedback loop regulate fructan hydrolase gene expression in Streptococcus mutans. Mol Microbiol. 2006 Oct, 62(1):187-200.
  • Abranches J, Candella MM, Wen ZT, Baker HV, Burne RA. Different roles of EIIABMan and EIIGlc in regulation of energy metabolism, biofilm development, and competence in Streptococcus mutans. J Bacteriol. 2006 Jun, 188(11):3748-56.
  • Wen ZT, Baker HV, Burne RA. Influence of BrpA on critical virulence attributes of Streptococcus mutans. J Bacteriol. 2006 Apr, 188(8):2983-92.
  • Ahn SJ, Wen ZT, Burne RA. Multilevel control of competence development and stress tolerance in Streptococcus mutans UA159. Infect Immun. 2006 Mar, 74(3):1631-42.
  • Laport MS, Dos Santos LL, Lemos JA, do Carmo F Bastos M, Burne RA, Giambiagi-Demarval M. Organization of heat shock dnaK and groE operons of the nosocomial pathogen Enterococcus faecium. Res Microbiol. 2006 Mar, 157(2):162-8.
  • Koo H, Seils J, Abranches J, Burne RA, Bowen WH, Quivey RG Jr. Influence of apigenin on gtf gene expression in Streptococcus mutans UA159. Antimicrob Agents Chemother. 2006 Feb, 50(2):542-6.
  • Abranches J, Lemos JA, Burne RA. Osmotic stress responses of Streptococcus mutans UA159. FEMS Microbiol Lett. 2006 Feb, 255(2):240-6.
  • Zeng L, Dong Y, Burne RA. Characterization of cis-acting sites controlling arginine deiminase gene expression in Streptococcus gordonii. J Bacteriol. 2006 Feb, 188(3):941-9.
  • Griswold AR, Jameson-Lee M, Burne RA. Regulation and physiologic significance of the agmatine deiminase system of Streptococcus mutans UA159. J Bacteriol. 2006 Feb, 188(3):834-41.
  • Lemos, J.A., Brown T.A. Jr, Abranches J., & Burne, R.A. (2005). Characteristics of Streptococcus mutans strains lacking the MazEF and RelBE toxin-antitoxin modules. FEMS Microbiol Lett, 253(2), 251-257.
  • Brown, T. A. Jr, Ahn, S. J., Frank R. N., Chen Y. Y., Lemos J. A., & Burne R. A. (2005). A hypothetical protein of Streptococcus mutans is critical for biofilm formation. Infect Immun, 73(5), 3147-51.
  • Ahn, S.J., Lemos, J.A., & Burne, R.A. (2005). Role of HtrA in growth and competence of Streptococcus mutans UA159. J Bacteriol, 187(9), 3028-38.
  • Wen, Z.T., Suntharaligham, P., Cvitkovitch, D.G., & Burne, R.A. (2005). Trigger factor in Streptococcus mutans is involved in stress tolerance, competence development, and biofilm formation. Infect Immun, 73(1), 219-25.
  • Lemos, J.A., Abranches, J., & Burne, R.A. (2005). Responses of cariogenic streptococci to environmental stresses. Curr Issues Mol Biol, 7(1), 95-107.
  • Antonelli, P.J., Lee, J.C., & Burne, R.A. (2004). Bacterial biofilms may contribute to persistent cochlear implant infection. Otol Neurotol, 25(6), 953-7.
  • Browngardt, C.M., Wen, Z.T., & Burne, R.A. (2004). RegM is required for optimal fructosyltransferase and glucosyltransferase gene expression in Streptococcus mutans. FEMS Microbiol Lett, 240(1), 75-9.
  • Abranches, J., Chen, Y.Y., & Burne, R.A. (2004). Galactose metabolism by Streptococcus mutans. Appl Environ Microbiol, 70(10), 6047-52.
  • Nascimento, M.M., Lemos, J.A., Abranches, J., Goncalves, R.B., & Burne, R.A. (2004). Adaptive acid tolerance response of Streptococcus sobrinus. J Bacteriol, 186(19), 6383-90.
  • Laport, M.S., Lemos, J.A., Bastos, M.F., Burne, R.A., & de Marval, M.G. (2004). Transcriptional analysis of the groE and dnaK heat-shock operons of Enterococcus faecalis. Res Microbiol, 155(4), 252-8.
  • Wen, Z.T., & Burne, R.A. (2004). LuxS-mediated signaling in Streptococcus mutans is involved in regulation of acid and oxidative stress tolerance and biofilm formation. J Bacteriol, 186(9), 2682-91.
  • Dong, Y., Chen, Y.Y., & Burne, R.A. (2004). Control of expression of the arginine deiminase operon of Streptococcus gordonii by CcpA and Flp. J Bacteriol, 186(8), 2511-4.
  • Griswold, A., Chen, Y.Y., Snyder, J.A., & Burne, R.A. (2004). Characterization of the arginine deiminase operon of Streptococcus rattus FA-1. Appl Environ Microbiol, 70(3), 1321-7.
  • Griswold, A.R., Chen, Y.Y., & Burne, R.A. (2004). Analysis of an agmatine deiminase gene cluster in Streptococcus mutans UA159. J Bacteriol, 186(6), 1902-4.
  • Lemos, J.A., Brown, T.A. Jr, & Burne, R.A. (2004). Effects of RelA on key virulence properties of planktonic and biofilm populations of Streptococcus mutans. Infect Immun, 72(3), 1431-40.

Tagged as: